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Yuanyuan Peng

Nanjing Medical University, P.R.China

Title: Effects of Mindfulness-based interventions(MBI) in patients with heart failure: A systematic review and meta-analysis

Biography

Biography: Yuanyuan Peng

Abstract

To systematically review the effects of mindfulness-based nursing interventions (including mindfulness-based stress reduction and mindfulness exercise, etc.) on negative emotions, quality of life, exercise tolerance and cardiac function in patients with heart failure.Methods Computerized retrieval of randomized controlled trials (RCT) of mindfulness- based interventions(MBI) applied in patients with chronic heart failure from PubMed,The Cochrane Library, EMbase, CINHAL,SinoMed,CNKI,WanFang Data,with the retrieval time limit starting from the inception until April 9,2019.In addition, assisted by manual retrieval and reference tracing.Two researchers independently screened the literatures according to the inclusion and exclusion criteria, extracted the data, evaluated the bias risk of the included literatures and cross- checked them. The results that could be quantitatively combined were meta-analyzed with RevMan 5.3 software.Results A total of 9 RCT articles involving 344 patients were included.Meta-analysis results showed that compared with usual care/usual exercise,MBI could improve patients’ depression [SMD = 0.30,95%CI(0.58, 0.03),P =0.03],the quality of life (MLHFQ) [WMD =7.09,95% CI (12.80, 1.38), P = 0.01],6 minutes walk test (6WMT) [WMD=24.54,95% CI (5.00, 44.09),P = 0.01], peak oxygen consumption (VO2) [WMD=5.45,95%CI(2.05,8.86),P= 0.002],heart rate(HR)[WMD=-4.87,95%CI(-9.85,0.10),P=0.05], but there was no statistically significant difference in the improvement of anxiety level (P >0.05).Conclusions Compared with usual care/usual exercise, mindfulness-based nursing interventions(MBI) could effectively improve the depression, quality of life, exercise tolerance and cardiac function of patients with heart failure, but the improvement on anxiety was not obvious.Due to the small number of studies included, there may be some bias existing,new RCTs need to be added to verify the results in the future